Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs.

Catalysis of ADP-ATP exchange by nucleotide exchange factors (NEFs) is central to the activity of Hsp70 molecular chaperones.Yet, the mechanism of interaction of this family of chaperones Desk Lamp with NEFs is not well understood in the context of the sequence evolution and structural dynamics of Hsp70 ATPase domains.We studied the interactions of

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A General Intelligent Optimization Algorithm Combination Framework with Application in Economic Load Dispatch Problems

Recently, a population-based intelligent optimization algorithm research has been combined with multiple algorithms or algorithm components in order to improve the HEPATO DR performance and robustness of an optimization algorithm.This paper introduces the idea into real world application.Different from traditional algorithm research, this paper imp

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Suicide Assasinations

Assassination, as an extreme form of political violence, is documented by historians as occurring ever since the early civilizations.The forms in which it would be applied depended on technological advances, but the perpetrator has always been KOMBU most exposed to the consequences of such an act.In the second half of the XIX century, with the deve

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